TY - JOUR AU - Yu, X-H. AU - Guo, W. AU - Zhang, J. AU - Ma, C. AU - Chu, A-J. AU - Wen, B-L. AU - Zhang, X. AU - Yan, X-Y. AU - Wu, C-M. AU - Wang, D-M. AU - Qu, Y-L. PY - 2017/03/31 Y2 - 2024/03/29 TI - Long non-codingRNA (lncRNA) TUG1 and the prognosis of cancer: a meta-analysis JF - Cellular and Molecular Biology JA - Cell Mol Biol (Noisy-le-grand) VL - 63 IS - 3 SE - Meta-Analysis DO - 10.14715/cmb/2017.63.3.7 UR - https://www.cellmolbiol.org/index.php/CMB/article/view/1236 SP - 36-39 AB - <p>Some studies assessed the association between lncRNA taurine-upregulated gene 1 (TUG1) and the survival in cancer. However, the results were inconclusive.  Therefore, we performed a meta-analysis to determine this association. We used the following electronic databases to search for eligible literature: PubMed, Embase, Chinese National Knowledge Infrastructure (CNKI) and Wanfang. We used ORs and 95% CIs to measure the association between TUG1 and the survival of cancer. There was no significant association between TUG1 and OS of cancer (HR=1.26, 95% CI=0.97-1.64). In the subgroup analysis by cancer type, significant association could be find in osteosarcoma (HR=1.72, 95% CI=1.27-2.32) and digestive system's tumors (HR=1.66, 95% CI=1.04-2.66). In conclusion, this meta-analysis study indicated that TUG1 might associate with the OS of osteosarcoma and digestive system's tumors.</p> ER -