Plant-food-derived bioactives: Key health benefits and current nanosystems as a strategy to enhance their bioavailability

Bahare Salehi; Célia F. Rodrigues; Aslı Can Karaca; Gözde Gülseren; Ezgi Åženol; Evren Demircan; Beraat í–zçelik; Sena Tutuncu; Farukh Sharopov; Javad Sharifi-Rad; Alfred Maroyi; Natália Martins

doi:10.14715/cmb/2020.66.4.28

Issue

Vol. 66 No. 4: Medicinal plants and natural products

Issue Published : June 23, 2020

Plant-food-derived bioactives: Key health benefits and current nanosystems as a strategy to enhance their bioavailability

https://doi.org/10.14715/cmb/2020.66.4.28

Bahare Salehi

Student Research Committee, School of Medicine, Bam University of Medical Sciences, Bam, Iran

Célia F. Rodrigues

LEPABE – Dep. of Chemical Engineering, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, s/n, 4200-465 Porto, Portugal

Aslı Can Karaca

Department of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Istanbul Technical University, Maslak, Istanbul 34469, Turkey

Gözde Gülseren

Department of Food Engineering, Chemical and Metallurgical Faculty, Istanbul Technical University, Maslak Istanbul, Turkey

Ezgi Åženol

Department of Food Engineering, Chemical and Metallurgical Faculty, Istanbul Technical University, Maslak Istanbul, Turkey

Evren Demircan

Department of Food Engineering, Chemical and Metallurgical Faculty, Istanbul Technical University, Maslak Istanbul, Turkey

Beraat í–zçelik

Department of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Istanbul Technical University, Maslak, Istanbul 34469, Turkey

Sena Tutuncu

Department of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Istanbul Technical University, Maslak, Istanbul 34469, Turkey

Farukh Sharopov

Department of Pharmaceutical Technology, Avicenna Tajik State Medical University, Rudaki 139, 734003, Dushanbe, Tajikistan

Javad Sharifi-Rad

Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Alfred Maroyi

Department of Botany, University of Fort Hare, Private Bag X1314, Alice 5700, South Africa

Natália Martins

Faculty of Medicine, University of Porto, Alameda Professor Herní¢ni Monteiro, 4200-319 Porto, Portugal

Corresponding Author(s) : Natália Martins

ncmartins@med.up.pt

Cellular and Molecular Biology, Vol. 66 No. 4: Medicinal plants and natural products
Article Published : June 25, 2020

Abstract

Natural products interest is gradually increasing worldwide. Plant-food-derived bioactives have a long history of use as a good source of ingredients for valuable medical usages. Plant-based foods consist of micro and macronutrients, and bioactive components, with health-promoting benefits. The handling of complex mixtures of plants has been methodically switched by therapies using a single isolated substance. The delivery of bioactive molecules in nanosystems is enhancing their bioavailability, it is much safer and cost-effective. However, there are many challenges in combining bioactive substances in nanocarrier materials. A discussion related with nanocarriers will be done in this review.

Keywords

Plant-food bioactives Nutrients Nanocarrier systems Bioavailability Drug delivery.

Salehi, B., Rodrigues, C. F., Can Karaca, A., Gülseren, G., Åženol, E., Demircan, E., í–zçelik, B., Tutuncu, S., Sharopov, F., Sharifi-Rad, J., Maroyi, A., & Martins, N. (2020). Plant-food-derived bioactives: Key health benefits and current nanosystems as a strategy to enhance their bioavailability. Cellular and Molecular Biology, 66(4), 232–242. https://doi.org/10.14715/cmb/2020.66.4.28