Human colon cancer HT-29 cell death responses to doxorubicin and Morus Alba leaves flavonoid extract
Corresponding Author(s) : S Fallah
Cellular and Molecular Biology,
Vol. 62 No. 3: Issue 3
The mechanistic basis for the biological properties of Morus alba flavonoid extract (MFE) and chemotherapy drug of doxorubicin on human colon cancer HT-29 cell line death are unknown. The effect of doxorubicin and flavonoid extract on colon cancer HT-29 cell line death and identification of APC gene expression and PARP concentration of HT-29 cell line were investigated. The results showed that flavonoid extract and doxorubicin induce a dose dependent cell death in HT-29 cell line. MFE and doxorubicin exert a cytotoxic effect on human colon cancer HT-29 cell line by probably promoting or induction of apoptosis.
Cell death Doxorubicin Flavonoid Viability.
Fallah, S., Karimi, A., Panahi, G., Gerayesh Nejad, S., Fadaei, R., & Seifi, M. (2016). Human colon cancer HT-29 cell death responses to doxorubicin and Morus Alba leaves flavonoid extract. Cellular and Molecular Biology, 62(3), 72–77. Retrieved from https://www.cellmolbiol.org/index.php/CMB/article/view/822
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